The review also introduces the reader to the emerging field of nonspecific metabolic disturbances and how they can lead to clues on mechanisms and treatment. Considering the large variety of metabolic disturbances identified in ASD, the authors question the extent to which any biomarker would accurately assess risk or guide individual treatment. The answer to the question may lie in the use of untargeted assays in order to broadly survey the multiple aspects of the metabolism of each individual patient. The use of biomarkers as metabolic measurements to improve ASD diagnosis and identification of underlying causes is a promising research tool in the hands of physicians but requires specialized skills for proper interpretation . Genomic scanning is beginning to elucidate the underlying genetic architecture that confers ASD susceptibility.
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Getting a clear diagnosis is essential to ensure that your child is receiving the right support. Despite some similarities, ADHD is not considered a spectrum disorder. One major difference between the two is that people with ADHD do not tend to lack socio-communicative skills. When in doubt, it’s always best to talk with a healthcare professional. Before investing in any alternative therapy, parents and caregivers should weigh the research and financial costs against any possible benefits. “Stimming” is a term used to describe self-stimulating behaviors, often involving repetitive motions or speech.
Possible causes and risk factors
Deficits in ASD are often linked to behavior problems, such as difficulties following directions, being cooperative, and doing things on other people’s terms. Symptoms similar to those of attention deficit hyperactivity disorder can be part of an ASD diagnosis. Oxidative stress, DNA damage and DNA repair have been postulated to play a role in the aetiopathology of both ASD and schizophrenia.
Science News About Autism Spectrum Disorder (ASD)
The authors analyzed the prospective trials conducted to date that studied the efficacy of the gluten- and casein-free diet in children with ASD . All of them compared gluten- and casein-free diet versus normal diet with a control group (2 double-blind randomized controlled trials, 1 double-blind crossover trial, 1 single-blind trial). In two of the studies, whose duration was 12 and 24 months, a significant improvement in ASD symptoms (efficacy rate 50%) was identified. In the other two studies, whose duration was 3 months, no significant effect was observed. The authors concluded that a longer duration of the diet may be necessary to achieve the improvement of the ASD symptoms. Other problems documented in the trials carried out include transgressions of the diet, small sample size, the heterogeneity of the participants and the possibility of a placebo effect. In the subset of people who have gluten sensitivity there is limited evidence that suggests that a gluten-free diet may improve some autistic behaviors.
Given the complexity of the disorder, and the fact that symptoms and severity vary, there are probably many causes. Because of the unique mixture of symptoms in each child, severity can sometimes be difficult to determine. It’s generally based on the level of impairments and how they impact the ability to function. To the always helpful Frontiers team whose organizational skills and understanding made this Research Topic possible. Kotte, A., Joshi, G., Fried, R., Uchida, M., Spencer, A., Woodworth, K. Y., et al. . Maria Montenegro, Caregiver Skills Training Master Trainer Maria shares how the University of Texas’ caregiver skills training program is benefiting Spanish-speaking families in the Rio Grande Valley. When everything becomes too much for an autistic person, they can go into meltdown or shutdown.